Evidence map›Paper›PMID 41491354›Full record

ArticleUpdates in surgery2026

Bridging the sensory gap: intraoperative lung ultrasound for deep pulmonary nodule localization in totally endoscopic robotic thoracic surgery.

Sebastiano Angelo Bastone, Alexandro Patirelis, Luciano Cialì Sposato, Cristiano Casciani, Karan Kumar, Federico Tacconi, Vincenzo Ambrogi

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Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sebastiano Angelo BastoneDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy.
Alexandro PatirelisDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy.ORCID http://orcid.org/0009-0009-7409-8470
Luciano Cialì SposatoDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy.
Cristiano CascianiDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy.
Karan KumarDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy.
Federico TacconiDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy.ORCID http://orcid.org/0000-0001-8850-5027
Vincenzo AmbrogiDepartment of Thoracic Surgery, Tor Vergata University Polyclinic, Viale Oxford, 81, 00133, Rome, Italy. ambrogi@med.uniroma2.it.ORCID http://orcid.org/0000-0002-8947-3175

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In robotic-assisted thoracic surgery (RATS), the absence of tactile feedback remains a critical limitation for intra-operative localization of small or deeply located pulmonary nodules. This study aimed to evaluate feasibility and safety of intra-operative lung ultrasound (ILU) as a real-time localization tool in this setting. We prospectively enrolled 26 patients undergoing totally endoscopic RATS for solid or part-solid pulmonary nodules located > 1 cm from the visceral pleura between February 2024 and February 2025. A linear extracorporeal ultrasound probe (Esaote LP 4-13) was used via the assistant port to identify the target lesion. Detection rate, localization time, resection margins, histology at frozen section and intra-operative outcomes were recorded. ILU successfully localized the target nodule in 25 out of 26 patients (96.1%). Median nodule diameter was 12 mm (IQR 9-14 mm), and median localization time was 12 min (IQR 10-15 min). All resected nodules had clear margins, with a median tumor-free distance of 11 mm (IQR 9-13 mm). Lobectomy was completed in 23 cases, while remaining patients underwent wedge resection alone due to indolent histology or intolerance to one-lung ventilation. No conversions to thoracotomy or peri-operative complications were observed. ILU proved to be a safe, accurate, and reproducible method for localizing deep pulmonary nodules in totally endoscopic RATS. By restoring the surgeon's spatial perception through imaging, ILU effectively compensates for the lack of tactile feedback in robotic surgery. This technique may allow for broader adoption of upfront robotic resections without pre-operative localization or biopsy.

Indexed as

Intra-operative lung ultrasound (ILU)Minimally invasive surgeryPulmonary nodule identificationRobotic assisted thoracic surgery (RATS)Thoracic surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.