Evidence map›Paper›PMID 41491238›Full record

ArticleScientific reports2026

Brain-infiltrating CD8 T cells retain functional activity to protect against acute Zika virus infection.

Jaehui Kim, Wooseong Lee, Do Yeon Kim, Keun Bon Ku, Young-Chan Kwon, Kyun-Do Kim, Chonsaeng Kim, Dae-Gyun Ahn, Seong-Jun Kim, Sungjun Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jaehui KimCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Wooseong LeeUntreatable Infectious Disease Institute, Kyungpook National University, Daegu, 41944, Republic of Korea.
Do Yeon KimCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Keun Bon KuCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Young-Chan KwonCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Kyun-Do KimCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Chonsaeng KimCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Dae-Gyun AhnCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Seong-Jun KimUntreatable Infectious Disease Institute, Kyungpook National University, Daegu, 41944, Republic of Korea.
Sungjun ParkCenter for Infectious Disease Vaccine and Diagnosis Innovation (CEVI), Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea. spark619@krict.re.kr.

Funding

Korea Research Institute of Chemical Technology KK2532-20
6 · The paper itself

Abstract

Zika virus (ZIKV) infection can cause severe neurological complications, yet the role of CD8

Indexed as

BrainCD8-Positive T-LymphocytesZika VirusZika Virus InfectionAdoptive TransferAnimalsMiceMice, Inbred C57BLMice, KnockoutProgrammed Cell Death 1 ReceptorReceptor, Interferon alpha-betaIfnar1 protein, mousePdcd1 protein, mouseProgrammed Cell Death 1 ReceptorReceptor, Interferon alpha-betaAcute infectionCD8+ T cellsCytotoxicityIfnar1 −/− mouse modelImmune cell infiltrationNeuroinflammationT cell traffickingZika virus (ZIKV)

Identifiers

PMID41491238
PMCPMC12873414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.