ArticleTrials2026
Photobiomodulation therapy in breast cancer-related acute radiodermatitis cases in Brazilian women: study protocol for a randomized controlled trial.
Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRadiodermatitis is one of the most common radiotherapy-related side effects, which can influence patients' quality of life and affect therapeutic efficacy. Photobiomodulation therapy (PBMT) appears as a low-cost technology, with significant results in the tissue repair process.
methodsIt is a triple blind randomized controlled trial. A total of 96 patients undergoing radiotherapy for breast cancer are estimated for the sample, which will be randomly assigned to a control group to receive a placebo and the institution's standard protocol (n = 48) or to an intervention group to receive PBMT, in addition to standard therapy (n = 48). The intervention consists of applying Laser Therapy EC (DMC™, São Carlos-SP, Brazil), with power of 100mW, continuous emission mode, red wavelength (660 ± 20 nm), fluence of 10.16 J/cm DISCUSSION: Photobiomodulation stands out for being a non-invasive and low-cost therapy that has not been associated with adverse events. It used to stimulate wound healing by promoting tissue repair, by reducing inflammation, by stimulating collagen synthesis, and relieving pain. Cientific literature have been highlighted PBMT as an effective tool in preventing or reducing the severity of radiodermatitis and its associated symptoms, which expected to be demonstrated with this ongoing study.
trial registrationBrazilian Clinical Trials Registry (ReBEC - Registro Brasileiro de Ensaios Clínicos) - Id. RBR-7gkw3d4; Universal Trial Number (UTN) - Id. U1111-1279-1686; Plataforma Brasil/Research Ethics Committee - Id. 5.788.390, registered on 24 August 2022. https://ensaiosclinicos.gov.br/rg/RBR-7gkw3d4 .
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.