Evidence map›Paper›PMID 41491131›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Semi-automated end-to-end quality control system for annotation data based on automated Cobb angle measurement.

Jingxi Su, Shufang Zhu, Jing Yuan, Junjie Xia, Haoyuan Qin, Guilin Chen, Terry Jianguo Zhang, Nan Wu

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Jingxi SuDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Shufang Zhu *School of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Jing YuanSchool of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Junjie XiaSchool of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Haoyuan QinSchool of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Guilin ChenDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Terry Jianguo ZhangDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Nan WuDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. dr.wunan@pumch.cn.

Funding

CAMS Innovation Fund for Medical Sciences 2021-I2M-1-051National High Level Hospital Clinical Research Funding 2022-PUMCH-C-033National High Level Hospital Clinical Research Funding 2022-PUMCH-D-004National Key Research and Development Program of China 2023YFC2507700the National Key Clinical Specialty Construction Project and the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences No. 2019PT320025
6 · The paper itself

Abstract

purposeThe field of automated scoliosis diagnosis necessitates large-scale data annotation; however, existing annotation practices are hampered by the lack of a systematic, end-to-end quality control framework. To address this gap, we aim to develop a Semi-Automated End-to-End QC (SAE-QC) System designed to ensure annotation accuracy while substantially accelerating the data collection pipeline and reducing operational costs. This system is expected to provide critical support for the construction of high-quality datasets and the development of reliable AI models in the domain of automated Cobb angle measurement.

methodsWe propose the SAE-QC System for medical image annotation, featuring core modules including a data assignment module with dual-blind annotation pairing medical and non-medical annotators, an annotation protocol QC module enforcing standardized guidelines through structured validation, and an annotation QC module performing comprehensive quality checks from format validation to multi-annotator consistency analysis. The system’s modular architecture ensures cross-platform compatibility and seamless integration across the entire annotation workflow from data distribution to expert adjudication, while maintaining flexibility for different medical imaging tasks and data formats.

resultsWe developed the SAE-QC System, comprising a Data Assignment Module, an Annotation Protocol QC Module, and an Annotation QC Module. By integrating automated algorithms with expert supervision, the system enables end-to-end management of both Cobb angle measurement and vertebral segmentation, significantly reducing error rates and improving data reliability. When applied to a dataset construction task, experimental results showed the following improvements in annotation quality: the abnormality rate for Cobb angle measurement decreased from 66% to 19%, measurement consistency improved by approximately 40%, and the abnormality rate for vertebral segmentation decreased from 27% to 2.9%, with a significant increase in overall accuracy.

conclusionThis study demonstrates that the SAE-QC system—integrating automated quality assurance with expert supervision—effectively enhances the reliability of medical image annotation, providing a practical framework for non-specialist teams to achieve high-quality annotations.

Indexed as

Data CurationImage Processing, Computer-AssistedScoliosisHumansQuality ControlCobb angle measurementData quality controlEnd-to-end systemMedical image annotationScoliosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.