Evidence map›Paper›PMID 41491096›Full record

SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in the treatment of hydrocephalus due to posterior fossa tumors in children: an updated meta-analysis.

Adriano M Lino-Filho, William Manoel da Silva Andrade, Walison José de Morais, Jonas Borges Santos Amorim, Mateus Neves Faria Fernandes, Gabriel Costa de O Teixeira Alvares, Bárbara A Morais, Jairo Porfírio de Oliveira Júnior, Paulo Ronaldo Jubé- Ribeiro

Abstract readMeta-AnalysisSystematic ReviewComparative Study
PubMed Publisher
In one paragraph

Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adriano M Lino-FilhoDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.
William Manoel da Silva AndradeDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil. williamcapellazzo@gmail.com.
Walison José de MoraisDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Jonas Borges Santos AmorimDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Mateus Neves Faria FernandesDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Gabriel Costa de O Teixeira AlvaresEvangelical University of Goiás, Anápolis, Goiás, Brazil.
Bárbara A MoraisDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Jairo Porfírio de Oliveira JúniorDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Paulo Ronaldo Jubé- RibeiroDivision of Neurosurgery, Department of Surgery, Clinics Hospital, Medical School, Federal University of Goiás, Goiânia, Goiás, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) in managing obstructive hydrocephalus secondary to posterior fossa tumors in pediatric patients.

methodsA systematic review and meta-analysis were conducted in accordance with PRISMA guidelines. Searches of PubMed, Cochrane, and Embase databases were performed on April 1, 2025. Primary outcomes included mortality and control of intracranial hypertension, while secondary outcomes encompassed infection and bleeding rates.

resultsThe search identified 417 studies, of which 12 met the inclusion criteria, encompassing 917 pediatric patients (360 ETV and 557 VPS). Ages ranged from 0 to 19 years, with 61% being male. No significant differences were observed between ETV and VPS in terms of mortality (OR 0.49; 95% CI 0.14-1.73; p = 0.27; I

conclusionETV and VPS demonstrated comparable outcomes regarding mortality, ICP control, and need for reoperation. ETV was associated with lower rates of infection and overall intracranial hemorrhage, although no difference was observed for intracerebral hemorrhage alone. Larger prospective studies are needed to confirm these findings.

Indexed as

HydrocephalusInfratentorial NeoplasmsNeuroendoscopyThird VentricleVentriculoperitoneal ShuntVentriculostomyAdolescentChildChild, PreschoolFemaleHumansInfantMaleTreatment OutcomeEndoscopic third ventriculostomyHydrocephalusPosterior fossa tumorsVentriculoperitoneal shunt

Identifiers

PMID41491096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.