ArticleProceedings of the National Academy of Sciences of the United States of America2026
Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter.
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8citing papers in PubMed
–field-weighted citation impact
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Who cites it
8 citing papers in PubMed.
- Structures of the human sodium-citrate cotransporter NaCT with and without substrates.Structure (London, England : 1993) · 2026Article
- Structures of the human sodium-citrate cotransporter NaCT with and without substrates.bioRxiv : the preprint server for biology · 2026Article
- Functional role of a structural water in the elevator domain of dicarboxylate transporter VcINDY.PNAS nexus · 2026Article
- Structural basis of metalloid transport by the arsenite efflux pump ArsB.Nature communications · 2026Article
- Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.Nature structural & molecular biology · 2025Article
- Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter.eLife · 2025Article
- Kinetic Diagram Analysis: A Python Library for Calculating Steady-State Observables of Biochemical Systems Analytically.Journal of chemical theory and computation · 2024Article
- Kinetic Diagram Analysis: A Python Library for Calculating Steady-State Observables of Biochemical Systems Analytically.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Colin D Kinz-ThompsonDepartment of Chemistry, Columbia University, New York, NY 10027.ORCID 0000-0002-2636-7893
Maria Louisa Lopez-RedondoDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016.
Christopher MulliganDivision of Natural Sciences, School of Biosciences, University of Kent, Canterbury, Kent CT2 7NH, United Kingdom.ORCID 0000-0001-5157-4651
David B SauerDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016.ORCID 0000-0001-9291-4640
Jennifer J MardenDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016.ORCID 0000-0002-7221-2454
Jinmei SongDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016.ORCID 0000-0001-8658-3590
Emad TajkhorshidDepartment of Biochemistry, Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-8434-1010
John F HuntDepartment of Biological Sciences, Columbia University, New York, NY 10027.ORCID 0000-0003-0034-5167
David L StokesDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016.ORCID 0000-0001-5455-8163
Joseph A MindellMembrane Transport Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892.ORCID 0000-0002-6952-8247
Da-Neng WangDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016.ORCID 0000-0002-6496-4699
Ruben L GonzalezDepartment of Chemistry, Columbia University, New York, NY 10027.ORCID 0000-0002-1344-5581
Funding
WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TAJKHORSHID, EMAD · 2012 to 2021
$19.0MResource for Macromolecular Modeling and VisualizationR24GM145965 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Emad Tajkhorshid · 2022 to 2026
$6.2MToolkit for High-Resolution Structure and Dynamics of Functional LipidsR01GM123455 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MORRISSEY, JAMES H., RIENSTRA, CHAD M · 2016 to 2020
$5.0MThe Structural Dynamics of Translation InitiationR01GM084288 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L · 2009 to 2022
$4.4MTransport Cycle and Inhibition of Human Na+-dicarboxylate Cotransporter NaDC3R01NS108151 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DANENG WANG · 2018 to 2026
$4.1MMolecular Mechanisms of Ion Transport - Equipment supplementR35GM144109 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI David L. Stokes · 2022 to 2026
$3.2MDynamics and mechanism of sodium-dependent carboxylate transportersR01DK135088 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Ruben L Gonzalez, Emad Tajkhorshid · 2023 to 2026
$2.6MThe Structural Dynamics of Translation and Translational ControlR35GM153724 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Ruben L Gonzalez · 2024 to 2026
$2.4MThe structural dynamics of ribosomal frameshifting and ribosome rescueR01GM137608 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L · 2020 to 2023
$1.6MStructural basis of the Ragulator-Rag GTPase complex as a platform for mTOR activation on the lysosomal surfaceR01GM121994 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2017 to 2020
$1.5MStructural and mechanistic studies of INDY proteinsR01DK099023 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2013 to 2016
$1.5MRational Engineering of Improved Protein CrystallizationR01GM127883 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HUNT, JOHN FRANCIS · 2018 to 2021
$1.3MAmerican Cancer Society (ACS) PF-17-135-01DOD | MHS | CDMRP | DOD Peer Reviewed Cancer Research Program (PRCRP) W81XH-16-1-015DOE | SC | Biological and Environmental Research (BER) DE-AC02-06CH11357DOE | SC | Brookhaven National Laboratory (BNL) N/AG. Harold and Leila Y. Mathers Foundation (Mathers Foundation) N/AHHS | NIH | National Institute of General Medical Sciences (NIGMS) GM084288HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM104601HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM121994HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM123455HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM127883HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM137608HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM144109HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) IntramuralHHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS108151HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) DK099023NIDDK NIH HHS R01 DK099023NIDDK NIH HHS R01 DK135088NIGMS NIH HHS P41 GM104601NIGMS NIH HHS R01 GM084288NIGMS NIH HHS R01 GM121994NIGMS NIH HHS R01 GM123455NIGMS NIH HHS R01 GM127883NIGMS NIH HHS R01 GM137608NIGMS NIH HHS R24 GM145965NIGMS NIH HHS R35 GM144109NIGMS NIH HHS R35 GM153724NINDS NIH HHS R01 NS108151Tess Foundation N/AUKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/V007424/1
Abstract
VcINDY, the sodium-dependent dicarboxylate transporter from
Indexed as
Bacterial ProteinsDicarboxylic Acid TransportersSodiumVibrio choleraeBiological TransportCrystallography, X-RayDicarboxylic AcidsFluorescence Resonance Energy TransferKineticsLipid BilayersMicroscopy, FluorescenceProtein BindingProtein MultimerizationProtein Structure, QuaternaryRecombinant ProteinsThermodynamicsBacterial ProteinsDicarboxylic AcidsDicarboxylic Acid TransportersLipid BilayersRecombinant ProteinsSodiumsecondary active transportersingle-molecule fluorescence resonance energy transferthermodynamic cycle efficiencytranslocation mechanism
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.