Evidence map›Paper›PMID 41490277›Full record

ArticleACS infectious diseases2026

Broad-Spectrum Naphthyl-Substituted Diaminoquinolines Inhibiting the AdeG Efflux Pump of

Rushikesh Tambat, Aysegul Saral Sariyer, Emrah Sariyer, Marcela Olvera, Mithila Farjana, Napoleon D'Cunha, John K Walker, Helen I Zgurskaya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rushikesh TambatDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Aysegul Saral SariyerDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Artvin Coruh University, 08000 Artvin, Turkey.
Emrah SariyerDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Artvin Coruh University, 08000 Artvin, Turkey.
Marcela OlveraDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Mithila FarjanaDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Napoleon D'CunhaSaint Louis University School of Medicine, St. Louis, Missouri 63110, United States.
John K WalkerSaint Louis University School of Medicine, St. Louis, Missouri 63110, United States.ORCID 0000-0002-8683-0026
Helen I ZgurskayaDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.ORCID 0000-0001-8929-4727

Funding

Transport across two membranes by AcrAB-TolC complexR01AI052293 · NIAID · UNIVERSITY OF OKLAHOMA NORMAN · PI ZGURSKAYA, HELEN I · 2003 to 2024
$7.7M
NIAID NIH HHS R01 AI052293
6 · The paper itself

Abstract

AdeFGH and AdeIJK, the two homologous multidrug efflux pumps of the resistance-nodulation-division superfamily of transporters, play distinct roles in

Indexed as

Acinetobacter baumanniiAminoquinolinesAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsQuinolinesAcinetobacter InfectionsDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsAminoquinolinesAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsQuinolinesAcinetobacter baumanniiefflux pump inhibitorsmultidrug efflux pumps

Identifiers

PMID41490277
PMCPMC12910579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.