ArticleCancer research communications2026
Treatment Delays and Survival Divides: Race, Sex, and Early-Onset Colorectal Cancer Disparities.
Article in Cancer research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sex-related differences in pathological characteristics of colorectal cancer: a retrospective study.Discover oncology · 2026Article
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5 authors.
Funding
Abstract
Our study examined the association between sex, race/ethnicity, and treatment timeliness with cause-specific survival (CSS) and overall survival (OS) among patients with early-onset colorectal cancer (EOCRC; diagnosed <50 years of age). We conducted a retrospective cohort analysis using data from the 2006 to 2020 Surveillance, Epidemiology, and End Results Program. Exposures were sex, race/ethnicity [non-Hispanic White (NHW), non-Hispanic Black (NHB), non-Hispanic Asian/Pacific Islanders (Asian/PI), non-Hispanic American Indian/Alaskan Native (AI/AN), and Hispanic], and treatment timeliness. Outcomes were CSS for colorectal cancer death and OS for any causes of death. Cox proportional models were applied. Among 79,090 patients with EOCRC, females (73.1% vs. 72.8% for males) were more likely to receive timely treatment and males had higher proportion of delay (7.5% vs. 6.9% for females; P < 0.001). Racial minorities had significantly greater delays (AI/AN 5.3%, Hispanic 4.2%, NHB 3.4%, Asian/PI 3.1% vs. NHW 2.2%; P < 0.05). Adjusted Cox models showed elevated colorectal cancer and overall mortality among males (14%-18% for CSS and 15%-20% for OS; P < 0.05) and NHB patients (23%-37% for CSS and 21%-34% for OS; P < 0.05) compared with females and NHW patients, respectively. Hispanic patients with no/unknown treatment had 22% higher colorectal cancer mortality [95% confidence interval (CI), 1.03-1.44] and 23% higher overall mortality (95% CI, 1.06-1.44). AI/AN/Asian/PI individuals had a 19% increased risk of overall mortality with delayed treatment (95% CI, 1-1.42). In conclusions, male and NHB patients had poorer CSS and OS regardless of treatment timing. Hispanic/AI/AN/Asian/PI patients faced higher mortality with delayed/undocumented treatment timing. SIGNIFICANCE: Targeted strategies should focus on improving timely access to high quality of care for AI/AN/Asian/PI patients while also addressing barriers beyond treatment timeliness, particularly for male and NHB patients.
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