Evidence map›Paper›PMID 41490062›Full record

ArticlePloS one2026

MedNeXt for accurate medical image classification and segmentation: A lightweight transformer-style convolutional neural network.

Ziqing Xue, Pengpeng Pi, Ziyi Liu, Zhaomu Zeng, Zhiwei Sun

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ziqing XueSchool of Clinical Medicine, Hebei University, Baoding, Hebei, P.R. China.
Pengpeng PiSchool of Intelligence Science and Technology, University of Science and Technology Beijing, Beijing, P.R. China.
Ziyi LiuSchool of Intelligence Science and Technology, University of Science and Technology Beijing, Beijing, P.R. China.ORCID https://orcid.org/0000-0002-2407-9599
Zhaomu ZengDepartment of Neurosurgery, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, P.R. China.
Zhiwei SunSchool of Clinical Medicine, Hebei University, Baoding, Hebei, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transformer-based deep learning architectures have achieved notable success across various medical image analysis tasks, driven by the global modeling capabilities of the self-attention mechanism. However, Transformer-based methods exhibit significant computational complexity and a large number of parameters, rendering them challenging to apply effectively in practical medical scenarios. Compared with Transformers, large-kernel Convolutional Neural Networks (CNNs) and Multi-Layer Perceptrons (MLPs) offer more efficient inference while retaining global contextual awareness. Therefore, we rethink the role of large-kernel CNNs and MLPs in medical image analysis and leverage them to replace the heavy self-attention operation, to strike a better balance between performance and efficiency. Specifically, we propose backbone models for medical image classification and segmentation, featured by three lightweight modules: Linear Attention Feed Forward Network (FFN) for enhancing lesion features, Spatial Encoding Module for integrating multi-scale lesion information, and Smooth Depth-Wise Convolution (DwConv) FFN for efficient interaction of channel features. Composed solely of lightweight convolutional and MLP operations, our method achieves a better balance between performance and efficiency, validated by the superior performances on five datasets with varying data scales and diseases, with 98.39% on SARS-COV2-CT-Scan, 98.12% on Monkeypox Skin Lesion Dataset, 98.58% on Large COVID-19-CT scan slice, 79.45% on Synapse and 91.28% on ACDC. The low computational cost, high-performance with limited training data, and generalizability to various of medical tasks make the proposed method a promising and practical solution for medical image classification and segmentation.

Indexed as

Image Processing, Computer-AssistedNeural Networks, ComputerAlgorithmsConvolutional Neural NetworksCOVID-19Deep LearningHumansSARS-CoV-2

Identifiers

PMID41490062
PMCPMC12768253

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.