Evidence map›Paper›PMID 41489762›Full record

ArticleRadiological physics and technology2026

Evaluation of dose rate and gantry speed variations in volumetric modulated Arc therapy optimization algorithms for a modern linear accelerator.

Venugopal Sundaram, David Khanna, Mohandass Palanisamy

Abstract readEvaluation Study
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Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Venugopal SundaramDivision of Physical Sciences, Karunya Institute of Technology and Sciences (Deemed University), Karunya Nagar, Coimbatore, Tamilnadu, 641114, India.ORCID http://orcid.org/0009-0006-8533-2670
David KhannaDivision of Physical Sciences, Karunya Institute of Technology and Sciences (Deemed University), Karunya Nagar, Coimbatore, Tamilnadu, 641114, India. davidkhanna@karunya.edu.ORCID http://orcid.org/0000-0001-5255-7212
Mohandass PalanisamyDepartment of Radiation Oncology, Fortis Hospital, Mohali, Punjab, 160062, India.ORCID http://orcid.org/0000-0002-3832-9616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study investigates the impact of gantry speed (GS) and dose rate (DR) variations on VMAT RapidArc plan quality and delivery using the Photon Optimizer (PO) and Progressive Resolution Optimizer (PRO) algorithms in the Varian TrueBeam LINAC. MATERIALS AND

methodsFive treatment sites (brain, head and neck, Hodgkin’s lymphoma, advanced lung, and cervix) were planned using PO and PRO algorithms. Plans were generated with varying GS (0.5 and 6.0 deg/s) and DR (100–600 MU/min) combinations, resulting in 24 plans per site. Plan quality was assessed using DVH parameters and isodose distributions. Technical delivery aspects, including MU/deg, total MU, DR, and GS patterns, were analyzed. Trajectory log files provided data on planned vs. delivered dose, gantry angle deviations, and MLC position deviations. Pre-treatment QA was performed using Portal dosimetry, with a 3%/3 mm gamma criterion.

resultsBoth PO and PRO algorithms demonstrated similar dose distributions and PTV coverage D95% (differences < 3%) across all sites and GS/DR combinations. Minor variations in OAR doses were observed. Maximum MU/deg limits varied with GS and DR levels, with PO showing higher limits at slower GS. PO generally exhibited higher MU/deg and DR compared to PRO. Gantry speed remained constant at the set value during delivery. Trajectory log analysis confirmed accurate dose delivery, with deviations in gantry angle and MLC positions within tolerances. Portal dosimetry yielded high gamma passing rates (> 98.6%) for both algorithms across all sites and GS/DR combinations, indicating accurate dose calculation and delivery.

conclusionThis study provides valuable insights into the technical aspects of VMAT delivery and supports the clinical use of both PO and PRO algorithms for a wide range of treatment sites and delivery conditions. Truebeam LINAC controller systems data confirmed any variation of GS and DS deliver better accuracy for both optimizers. Current Truebeam platform LINAC can deliver any extreme mechanical limits without causing or reducing accuracy plans can be delivered very accurately.

Indexed as

AlgorithmsParticle AcceleratorsRadiation DosageRadiotherapy, Intensity-ModulatedHumansNeoplasmsRadiotherapy DosageRadiotherapy Planning, Computer-AssistedTime FactorsAlgorithmsDose rateGantry speedPhoton optimizerProgressive resolution optimizerRapidarcTruebeamVMAT

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.