ArticleJournal of medicinal chemistry2026
Modeling Metabolite Kinetics with a Partial Differential Equation-Based Hepatic Sinusoidal Model and MALDI-Mass Spectrometry Imaging of Verapamil and Its Metabolites.
Article in Journal of medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
Abstract
A partial differential-equation-based liver model incorporating sinusoidal blood flow, interstitial fluid, cytosol, and lipid partitioning was developed. Reported multi-indicator dilution data were used to parametrize the model, which was interfaced to whole-body compartmental models and was stable for long simulation times. Using intrinsic clearances from the dispersion model with closed boundary conditions, the model reproduces
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Registered trials
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