Evidence map›Paper›PMID 41489207›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Direct versus referred admission to the maternity hospital due to preeclampsia: Does it influence pregnancy outcomes?

Juliana da-Costa-Santos, Guilherme F Borges, Vitor L V Reis, Rodolfo R Japecanga, Maykon A Carvalho, Ana Julia G Oliveira, Laura C Vinchi, Arthur B P Righi, Jussara Mayrink, Fernanda G Surita and 4 more

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Direct versus referred admission to the maternity hospital due to preeclampsia: Does it influence pregnancy outcomes?International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Juliana da-Costa-SantosDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0002-2708-350X
Guilherme F BorgesDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Vitor L V ReisDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Rodolfo R JapecangaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Maykon A CarvalhoDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Ana Julia G OliveiraDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Laura C VinchiDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Arthur B P RighiPontifical Catholic University of Campinas, Campinas, Brazil.
Jussara MayrinkDepartment of Obstetrics and Gynecology, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Fernanda G SuritaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
José Paulo de Siqueira GuidaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Renato T SouzaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
José G CecattiDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Maria Laura CostaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0001-8280-3234

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 408407/2021-2Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.896655/2023-00Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/09937-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/13456-4Programa Institucional de Bolsas de Iniciação Científica - PIBIC/CNPq-UNICAMP
6 · The paper itself

Abstract

objectivesThis study describes maternal and perinatal outcomes of women with preeclampsia (PE) according to hospital admission characteristics: referral from lower complexity settings or directly admitted at the reference hospital.

methodsThis is a cross-sectional study considering women with PE who were admitted for childbirth between September 2019 and August 2021, at a Brazilian university hospital. Women were divided into hospitalized at the tertiary center or referred women (from facilities in the region). The main outcome measures were need for magnesium sulfate (proxy for severity), mean gestational age (GA) at childbirth, 5-min Apgar score <7, birthweight, and maternal and perinatal deaths.

resultsThere were 3914 childbirths, with 428 with PE (10.9%). Among PE cases, 37 (8.6%) were referred cases. Magnesium sulfate was used in 89.2% of the referred women and 44.8% of non-referred (P < 0.001). The mean GA at childbirth differed significantly between groups (referred cases: 33.6 ± 3.27 weeks vs. 36.1 ± 2.97 weeks, P < 0.001). Five-minute Apgar <7 was more frequent among referred cases (13.9% vs. 4.1%, P = 0.03). There were no maternal deaths and no differences in perinatal deaths between groups. Newborns from referred mothers had lower mean birthweight (2150 ± 946 vs. 2730 ± 800 g, P < 0.001) and needed more intensive care (72.2 vs. 34.9%, P < 0.001).

conclusionReferred women with PE had worse maternal and perinatal outcomes than those who were directly hospitalized in the tertiary center, which highlights the importance of timely diagnosis and delays associated to referral of women with PE.

Indexed as

Hospitals, MaternityPatient AdmissionPre-EclampsiaPregnancy OutcomeReferral and ConsultationAdultApgar ScoreBirth WeightBrazilCross-Sectional StudiesFemaleGestational AgeHospitalizationHumansInfant, NewbornMagnesium SulfateMagnesium Sulfatedelivery of health careperinatal carepreeclampsiapregnancy complicationsreferrals

Identifiers

PMID41489207
PMCPMC13173636

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.