ArticleFrontiers in surgery2025
Impact of a standardized perioperative care protocol on functional and radiographic outcomes following transforaminal lumbar interbody fusion for degenerative spondylolisthesis: a 2-year randomized controlled trial.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07104448 (Impact of a Standardized Perioperative Care Protocol on Functional and Radiographic Outcomes Following Transforaminal Lumbar Interbody Fusion for Degenerative Spondylolisthesis), which is not on this map. Not yet cited in PubMed.
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Impact of a Standardized Perioperative Care Protocol on Functional and Radiographic Outcomes Following Transforaminal Lumbar Interbody Fusion for Degenerative Spondylolisthesis: A Randomized Controlled Trial
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5 authors.
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Abstract
Objective: To evaluate the efficacy of a comprehensive, standardized perioperative care protocol (SPCP) vs. conventional care on functional recovery, radiographic outcomes, and quality of life in patients undergoing transforaminal lumbar interbody fusion (TLIF) for low-grade degenerative lumbar spondylolisthesis. Methods: This was a single-center, prospective, randomized controlled trial conducted between January 2018 and June 2023. A total of 382 patients were randomized to either the SPCP group ( Results: At the 2-year follow-up, the SPCP group demonstrated a significantly greater improvement in ODI scores compared to the control group (mean change: -30.0 vs. -25.5 points; mean difference: -4.5, 95% CI: -5.9 to -3.1; Conclusion: Implementation of a comprehensive SPCP significantly enhances long-term functional recovery, improves radiographic fusion rates, elevates quality of life, and reduces complications and hospital stay for patients undergoing TLIF for degenerative spondylolisthesis. This protocol-driven approach represents a valuable strategy for optimizing patient outcomes and healthcare efficiency in spine surgery. Clinical trial registration: ClinicalTrials.gov, identifier NCT07104448.
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