Evidence map›Paper›PMID 41488831›Full record

ArticleAnnals of gastroenterological surgery2026

Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High-Volume Center.

Daisuke Asano, Toshitaka Sugawara, Keiichi Akahoshi, Shotaro Gan, Shohei Motohashi, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Atsushi Kudo, Daisuke Ban

Abstract read
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In one paragraph

Article in Annals of gastroenterological surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daisuke AsanoDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-0867-7572
Toshitaka SugawaraDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Keiichi AkahoshiDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Shotaro GanDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Shohei MotohashiDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Shuichi WatanabeDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Yoshiya IshikawaDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-3348-5652
Hiroki UedaDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Atsushi KudoDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.
Daisuke BanDepartment of Hepatobiliary and Pancreatic Surgery Institute of Science Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0003-0868-8519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgical resection for neuroendocrine liver metastasis (NELM) is the key to long survival; however, the indications remain unclear due to the high recurrence rate. We aimed to identify candidates who would benefit from surgical resection for NELM. Methods: Patients with NELM treated at our institution from January 2005 to December 2020 were included. Neuroendocrine carcinoma (NEC) was excluded. Risk factors for overall survival (OS) and recurrence-free survival (RFS) were analyzed. The cut-off value for the number of NELM predicting poor RFS was determined by minimum Results: Of the total 126 patients, 67 patients underwent liver resection. The median follow-up time from the date of initial diagnosis of NELM was 4.3 years. Surgical resection and NET-G1/2 were associated with good OS in multivariate analysis ( Conclusion: This study suggests that fewer than 8 liver metastases and NET-G1/2 are indications for surgical resection in patients with NELM considering the RFS. Surgical resection for patients with 8 or more liver metastases or NET-G3 needs deliberate selection.

Indexed as

indicationNELMneuroendocrine neoplasmneuroendocrine tumorsurgery

Identifiers

PMID41488831
PMCPMC12757151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.