Evidence map›Paper›PMID 41488820›Full record

ArticleGastroenterology research2025

Metabolic Regulatory Mechanism of Gastric Motility by Acetylcholine.

Jun Young Lee, Hyo-Yung Yun, Dae Hoon Kim, Seung Myoung Son, Woong Choi, Hun Sik Kim, Ki Bae Kim, Seung Heun Kang, Hahn Jin Jung, Dong Wook Lee and 5 more

Abstract read
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In one paragraph

Article in Gastroenterology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jun Young LeeDepartment of Internal Medicine, College of Medicine, Chungbuk National University (CBNU), Chungbuk 28644, Korea.
Hyo-Yung YunDepartment of Surgery, CBNU, Chungbuk 28644, Korea.
Dae Hoon KimDepartment of Surgery, CBNU, Chungbuk 28644, Korea.
Seung Myoung SonDepartment of Pathology, CBNU, Cheongju, Chungbuk 28644, Korea.
Woong ChoiDepartment of Pharmacology, College of Medicine, CBNU, Chungbuk 28644, Korea.
Hun Sik KimDepartment of Pharmacology, College of Medicine, CBNU, Chungbuk 28644, Korea.
Ki Bae KimDepartment of Internal Medicine, CBNU, Chungbuk 28644, Korea.
Seung Heun KangDepartment of ENT, CBNU, Chungbuk 28644, Korea.
Hahn Jin JungDepartment of ENT, CBNU, Chungbuk 28644, Korea.
Dong Wook LeeDepartment of ENT, CBNU, Chungbuk 28644, Korea.
Wen-Xie XuDepartment of Physiology, College of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Kyung-Kuk HwangDepartment of Internal Medicine, College of Medicine, Chungbuk National University (CBNU), Chungbuk 28644, Korea.
Sang Jin LeeDepartment of Physiology, College of Medicine, CBNU, Chungbuk 28644, Korea.
Young Chul KimDepartment of Physiology, College of Medicine, CBNU, Chungbuk 28644, Korea.
Jang-Whan BaeDepartment of Internal Medicine, College of Medicine, Chungbuk National University (CBNU), Chungbuk 28644, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acetylcholine (ACh), a crucial neurotransmitter for gastric contractions, induces triphasic contraction in stomach. However, the precise mechanism of ACh-induced phasic contractions (AiPCs) remains unclear. Recent data suggest the chloride channel (Cl Methods: Isolated gastric smooth muscle strips from mice and humans were used to record isometric contraction. The subunits of Cl Results: Niflumic acid and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS), known to block the Cl Conclusions: This is the first study to demonstrate that suppression of energy metabolism reduces AiPC through activation of K

Indexed as

Acetylcholine-induced phasic contractionATP-sensitive potassium channelsCalcium-activated chloride channelsEnergy metabolismGastric motility

Identifiers

PMID41488820
PMCPMC12758062

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.