Evidence map›Paper›PMID 41488778›Full record

ArticleiScience2026

Viral load dependent cellular heterogeneity in Trichomonas vaginalis at the single cell level.

Hong-Wei Luo, Seow-Chin Ong, Jhen-Wei Syu, Chih-Yu Tsai, Po-Jung Huang, Chi-Ching Lee, Yuan-Ming Yeh, Rose Lin, Cheng-Hsun Chiu, Petrus Tang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Impact of pH andProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hong-Wei LuoGraduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan 333, Taiwan.
Seow-Chin OngDepartment of Parasitology, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Jhen-Wei SyuGraduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan 333, Taiwan.
Chih-Yu TsaiDepartment of Parasitology, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Po-Jung HuangDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan District, Taoyuan 333, Taiwan.
Chi-Ching LeeGenomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Yuan-Ming YehGenomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Rose LinDepartment of Parasitology, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Cheng-Hsun ChiuMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Petrus TangDepartment of Parasitology, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichomonasvirus (TVV) is a double-stranded RNA virus that persistently infects Trichomonas vaginalis, a protozoan parasite responsible for the most common non-viral sexually transmitted infection. While TVV has been implicated in modulating parasite biology and drug sensitivity, the extent and significance of viral heterogeneity remain unclear. Using ultra-deep single-cell RNA sequencing (scRNA-seq) on three TVV-positive

Indexed as

OmicsParasitologyVirology

Identifiers

PMID41488778
PMCPMC12757555

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.