Evidence map›Paper›PMID 41488701›Full record

ArticleOpen forum infectious diseases2026

Real-world Use of Molecular Point-of-care Testing for Sexually Transmitted Infections (STIs) in the Emergency Department: Why It Matters for Acute Care Management.

Gaby Dashler, Kendall Maliszewski, Mustapha Saheed, Edana Mann, Nyah Johnson, Spencer J Mann, Tracy Colburn, William Clarke, Charlotte A Gaydos, Yukari C Manabe and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Point-of-care Tests for Chlamydia trachomatis and Neisseria gonorrhoeae: Review of the Literature.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gaby DashlerDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Kendall MaliszewskiDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Mustapha SaheedDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Edana MannDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Nyah JohnsonDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Spencer J MannDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Tracy ColburnDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
William ClarkeDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Charlotte A GaydosDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yukari C ManabeDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
K Davina FrickDepartment of Operations Management and Business Analytics, Carey Business School, Johns Hopkins University, Baltimore, Maryland, USA.
Richard E RothmanDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Yu-Hsiang HsiehDepartment of Emergency Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-1616-8014

Funding

LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Susan Anne Tuddenham · 2007 to 2026
$34.6M
NIAID NIH HHS P30 AI094189NIAID NIH HHS UM1 AI068613NIBIB NIH HHS U54 EB007958
6 · The paper itself

Abstract

Background: Point-of-care (POC) polymerase chain reaction (PCR) tests for sexually transmitted infections (STIs) represent a potential paradigm shift for emergency department (ED) management of patients with suspected STIs, given there are now Food and Drug Administration-cleared POC tests that permit definite rapid diagnosis and result-driven care. Methods: A quasi-experimental real-world implementation study was conducted in an urban ED, comparing two approaches for female STI testing for Results: Of 627 patients, 340 received central laboratory testing and 287 received ED POC; ED POC resulted in a significant decrease in LOS by 76 minutes or 9.3% (95% confidence interval [CI], -16.3% to -1.7%; Discussion: Compared to traditional STI testing, POC PCR testing significantly shortened ED LOS, allowed for organism-specific targeted treatment, and reduced overtreatment of CT and NG infections.

Indexed as

antibiotic over- and under-treatmentemergency departmentemergency department length of staymolecular point-of-care testsexually transmitted infections (STIs)

Identifiers

PMID41488701
PMCPMC12757586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.