Evidence map›Paper›PMID 41488575›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2025

Anticoagulant Therapy in Neonatal Acute Infectious Peritonitis Based on the TAT, PIC, t-PAIC, and sTM: A New Case Series.

Wenya Wang, Yue Gao, Yan Qiao, Yang Wu, Jiao Li, Li Zhang

Abstract readCase Reports
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenya WangDepartment of Pediatrics, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China.ORCID 0009-0006-6663-8244
Yue GaoDepartment of Pediatrics, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China.
Yan QiaoDepartment of Pediatrics, Shanxi Coal Central Hospital, Taiyuan, Shanxi, China.
Yang WuDepartment of Pediatric Surgery, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Jiao LiDepartment of Pediatrics, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China.
Li ZhangDepartment of Pediatrics, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China.ORCID 0000-0001-5233-5708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal acute peritonitis is a leading cause of morbidity and mortality and poses challenges that demand prompt diagnosis and treatment, particularly in infants with disseminated intravascular coagulation. Here, we report a case series of four infants with acute peritonitis caused by necrotizing enterocolitis, gastrointestinal perforation, and meconium peritonitis. Laboratory tests for thrombin-antithrombin III complex (TAT), plasmin-α2-plasmin inhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (t-PAIC) suggested the activation of the coagulation system followed by treatment with anticoagulant therapy in these infants. Overall, TAT, PIC, t-PAIC, and sTM may guide anticoagulant therapy, offering prospects for improving the outcomes in neonates with acute peritonitis.

Indexed as

acute peritonitishypercoagulabilityinfectious diseasesLMW-heparinPICsTMTATt-PAIC

Identifiers

PMID41488575
PMCPMC12757086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.