Evidence map›Paper›PMID 41488548›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Diagnostic Performance of High-Frequency Ultrasound and Ultra-High-Frequency Ultrasound in Distinguishing Dermatofibrosarcoma Protuberans from Dermatofibroma: A 15-year Period Retrospective Analysis.

Guiwu Chen, Haibo Luo, Wenqin Liu, Xiaomin Liao, Jiaxin Meng, Zhongxian Qiu, Xiaoling Leng

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guiwu Chen *Department of Ultrasound, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.ORCID 0000-0003-2805-9007
Haibo Luo *Department of Ultrasound, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.
Wenqin LiuDepartment of Ultrasound, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.
Xiaomin LiaoDepartment of Pathology, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.
Jiaxin MengDepartment of Ultrasound, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.
Zhongxian QiuDepartment of Ultrasound, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.
Xiaoling LengDepartment of Ultrasound, The Tenth Affiliated Hospital, Southern Medical University, Dongguan People's Hospital, Dongguan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Dermatofibrosarcoma protuberans (DFSP) and dermatofibroma (DF) are cutaneous lesions with overlapping clinical features, often requiring histopathological confirmation. This study aims to evaluate and compare the diagnostic utility of high-frequency ultrasound (HFUS) and ultra-high-frequency ultrasound (UHFUS) in distinguishing these two entities over 15-year period. Methods: A retrospective analysis was conducted on 334 patients (127 DFSP, 207 DF) with pathologically confirmed diagnoses. HFUS or UHFUS was used to assess lesion characteristics, including demographics, location, size, morphology, echogenicity, homogeneity, posterior acoustic features, and vascularity. Univariate and multivariate logistic regression analyses were performed to identify significant predictors. Results: DFSP patients were significantly older than DF patients (40.99 years vs 34.00 years; Conclusion: HFUS and UHFUS demonstrates strong diagnostic utility in differentiating DFSP from DF based on key clinical and sonographic features. These findings support the use of HFUS and UHFUS as a valuable non-invasive tool for preoperative diagnosis. Future studies should validate these criteria in multi-center settings and exploring artificial intelligence integration to further enhance diagnostic accuracy and standardization.

Indexed as

dermatofibromadermatofibrosarcoma protuberanshigh-frequency ultrasoundpathological examinationultra-high-frequency ultrasound

Identifiers

PMID41488548
PMCPMC12756956

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.