ArticleRSC advances2025
Liposome nanoparticles with photothermal effect for the treatment of bacterial infectious periodontitis.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Spatially Confined/Ligand-Directed Ultrabright NIR-AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Bioorthogonal aggregation-induced emission nanoprobes for targeted photodynamic eradication of Gram-negative pathogens in periodontitis.Materials today. Bio · 2026Article
- Local drug delivery systems for the periodontal microenvironment: from barrier penetration to multilevel synergy.Frontiers in pharmacology · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel strategy is imperative to address the limitations of conventional mechanical and pharmacological periodontal treatments, which are constrained by the inherent difficulty in completely eradicating plaque biofilm and the tendency for bacterial resistance to develop. Photothermal therapy (PTT) emerges as an innovative therapeutic approach for managing periodontitis, offering the distinct advantage of circumventing drug resistance. Furthermore, Near-Infrared-II (NIR-II) guided PTT enhances therapeutic efficacy and provides a viable method for eliminating bacteria in deep periodontal pockets. In this study, we encapsulated 2TT-oC6B, a fluorophore with aggregation-induced emission (AIE) properties, into liposomes to make AIE nanoparticles (2TT-oC6B@LIP), thereby improving their water dispersibility and enabling their use as photothermal agents for treating periodontitis. Upon exposure to 808 nm NIR irradiation, 2TT-oC6B@LIP effectively eradicated a broad spectrum of periodontal pathogens, including both Gram-positive
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Registered trials
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