Evidence map›Paper›PMID 41488478›Full record

ArticleFrontiers in cellular and infection microbiology2025

Body site-specific micro- and lactobiota in genitourinary infections during pregnancy.

Siiri Kõljalg, Epp Sepp, Jelena Štšepetova, Eva-Liina Süüden, Tiia Reimand, Madis Jaagura, Andres Salumets, Reet Mändar

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siiri KõljalgDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
Epp SeppDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
Jelena ŠtšepetovaDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
Eva-Liina SüüdenInstitute of Clinical Medicine, Department of Obstetrics and Gynecology, University of Tartu, Tartu, Estonia.
Tiia ReimandInstitute of Clinical Medicine, Department of Clinical Genetics, University of Tartu, Tartu, Estonia.
Madis JaaguraInstitute of Genomics, University of Tartu, Tartu, Estonia.
Andres SalumetsCelvia Competence Centre (CC), Tartu, Estonia.
Reet MändarDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Immunological, metabolic, and hormonal changes occur during pregnancy, which can affect the composition and function of the microbiota in diverse body sites. These changes can influence pregnancy outcomes and the health of the mother and baby. We aimed to characterize the microbiota of pregnant women across various body sites and examine the clinical and population-specific factors associated with its composition. The role of lactobacilli in genitourinary infections during pregnancy was analyzed as well. Material and methods: One hundred and five pregnant women with gestational age between 15 and 20 weeks were recruited from the Women's Clinic of Tartu University Hospital, Estonia. Microbiota samples of the cervix (C, Results: Firmicutes was the most common phylum in all investigated locations, with a mean proportion of over 50%. Conclusions: The microbiota of pregnant women is linked to health profile and lifestyle factors and varies in different body regions; however, it is remarkably similar in the cervix and vagina. Higher abundance of

Indexed as

Female Urogenital DiseasesLactobacillusMicrobiotaPregnancy Complications, InfectiousAdultCervix UteriFemaleHumansMouthPregnancyRectumUrineVaginaYoung Adultgenitourinary infectiongenitourinary microbiotaoral microbiotapregnancyrectal microbiota

Identifiers

PMID41488478
PMCPMC12757402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.