Evidence map›Paper›PMID 41488472›Full record

ReviewMedComm2026

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics.

Yunzheng Yan, Yaqin Sun, Guangyan Sun, Cheng Niu, Xinyuan Zhao, Ming Zhao, Tongyao Liu, Suyue Zhang, Hui Zhai, Ankang Liu and 5 more

Abstract readReview
In one paragraph

Review in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yunzheng YanState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Yaqin SunState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Guangyan SunState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Cheng NiuState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Xinyuan ZhaoState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Ming ZhaoState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Tongyao LiuState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Suyue ZhangState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Hui ZhaiState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Ankang LiuState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Shouzhi YuState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Shuyuan PanState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases Beijing Institute of Biological Products Company Limited Beijing China.
Wu ZhongNational Engineering Research Center for the Emergency Drug Beijing China.
Yuntao ZhangState Key Laboratory of Novel Vaccines for Emerging Infectious Diseases China National Biotec Group Company Limited Beijing China.
Song LiNational Engineering Research Center for the Emergency Drug Beijing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since 2022, mpox epidemics have been sustaining and escalating over the world, posing a significant public health challenge. While significant progress has been made in diagnostic methodologies, prophylactic vaccines, and therapeutic interventions to mitigate monkeypox virus (MPXV) infection, scientific understanding of MPXV and related orthopoxviruses continues to evolve progressively. In order to keep pace with recent advancements, herein we review progress in mpox research from five key perspectives. This article first summarizes the latest epidemiological profiles, incorporating different viral lineages globally and in China, while highlighting their evolutionary history and distinct clinical characteristics. The virological profiles of MPXV shed light on its complete infectious lifecycle and the formation of distinct virus particle types. Clinically approved classical detection methods and emerging novel testing techniques are provided, establishing a framework for early diagnosis of mpox patients. The efficacy and safety of both licensed vaccines and those under development are analyzed to underscore their value in preventing mpox infection. Additionally, progress in approved and newly identified potential therapeutic agents is summarized and discussed, aiming to provide insights for further drug development and clinical treatment strategies.

Indexed as

diagnosisepidemiologymonkeypox virustherapeuticsvaccinevirology

Identifiers

PMID41488472
PMCPMC12757852

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.