The safety and efficacy of non-emergent percutaneous coronary intervention via distal radial artery access in patients with acute coronary syndrome.

Objective: The objective of this study was to evaluate the efficacy and safety of distal transradial access (dTRA) for non-emergent percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). Methods: This single-center, randomized controlled study was conducted in the Department of Cardiology at Inner Mongolia Medical University Affiliated Hospital between January and July 2025. Patients with ACS who met the inclusion criteria were assigned to the distal transradial access (dTRA) group or the conventional transradial access (TRA) group at a 1:1 ratio using a random number table method. Clinical baseline data and operation data were collected. Radial artery Doppler ultrasound was performed 24 h and 30 days after PCI to detect radial artery occlusion (RAO). Results: A total of 106 patients were included in the study, with no significant differences in clinical baseline data and operation data between the two groups. The incidence of RAO at 24 h after PCI in the dTRA group was significantly lower than that in the TRA group (1.9% vs. 15.1%, Conclusions: For ACS patients undergoing non-emergent PCI, dTRA is a safe and effective approach. dTRA significantly reduced the incidence of RAO at 24 h after PCI and had a shorter hemostasis time, without affecting the interventional procedure.