Evidence map›Paper›PMID 41488453›Full record

ArticleJournal of Brown hospital medicine2025

Post-Infectious Acquired Hemophilia A: A Case Report and Review of the Literature.

Jandir Mendonça Nicacio, Christian Mangueira Monteiro de Araújo Júnior, Naiara de Souza Barros, Paulo Inocêncio da Fonseca Cufua, André Luis Magalhães Fernandes

Abstract readCase Reports
In one paragraph

Article in Journal of Brown hospital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jandir Mendonça NicacioDepartment of Medicine Federal University of São Francisco Valley.ORCID https://orcid.org/0000-0001-9139-2414
Christian Mangueira Monteiro de Araújo JúniorDepartment of Medicine Federal University of São Francisco Valley.ORCID https://orcid.org/0009-0009-2970-2608
Naiara de Souza BarrosDepartment of Medicine Federal University of São Francisco Valley.ORCID https://orcid.org/0009-0008-3682-2934
Paulo Inocêncio da Fonseca CufuaDepartment of Medicine Federal University of São Francisco Valley.ORCID https://orcid.org/0009-0006-2861-9202
André Luis Magalhães FernandesDivision of Hematology Hospital Regional Juazeiro, Juazeiro (BA), Brazil.ORCID https://orcid.org/0000-0002-5848-4883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 52-year-old man with no personal or family history of bleeding presented with extensive hematomas and skin bruising following prolonged antibiotic use. Initial laboratory evaluation revealed coagulopathy, with an elevated activated partial thromboplastin time and mild anemia. Mixing studies and factor assays confirmed the diagnosis of acquired hemophilia A, characterized by low factor VIII levels and high-titer factor VIII inhibitors. The patient was initiated on corticosteroids and cyclophosphamide, leading to gradual improvement in both bleeding symptoms and coagulation parameters. Comprehensive evaluations excluded autoimmune diseases and malignancies, supporting the conclusion that the condition was linked to prolonged antibiotic use. The patient continues to be in clinical remission after targeted therapy.

Indexed as

Acquired hemophilia ACoagulopathyFactor VIII inhibitors

Identifiers

PMID41488453
PMCPMC12764325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.