Evidence map›Paper›PMID 41488442›Full record

ArticleJournal of Brown hospital medicine2025

Dual Antibody Positive Rheumatoid Feet.

Michael E Lazarus, Tyler B Larsen, Jason D Napolitano, Estebes A Hernandez

Abstract readCase Reports
In one paragraph

Article in Journal of Brown hospital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael E LazarusDepartment of Medicine University of California, Los Angeles.ORCID https://orcid.org/0000-0003-2654-9221
Tyler B LarsenDepartment of Medicine University of California, Los Angeles.ORCID https://orcid.org/0000-0001-6633-3797
Jason D NapolitanoDepartment of Medicine University of California, Los Angeles.
Estebes A HernandezDepartment of Medicine University of California, Los Angeles.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 86-year-old man presented with severe, debilitating, dual antibody positive rheumatoid arthritis associated joint deformities of his upper and lower extremities. These developed over twenty years but were progressive and debilitating. They began in the forefoot and eventually progressed to mid and hindfoot bilaterally. Examination of his lower extremities revealed severe bilateral hallux valgus deformities, traumatic pes planus deformity, right foot metatarsal head subluxation, and bilateral claw and hammer toes. Relentless progression of his lower extremity pain, joint destruction and significant gait limitation was due to a constellation of factors including ongoing tobacco use, dual antibody positivity and intolerance based on side effects to multiple targeted biologic disease-modifying antirheumatic (DMARD) medications including infliximab, etanercept, golimumab and tofacitinib.

Indexed as

ankle fusionanti-citrullinated protein antibodyclaw toeDual antibody positiveHallux ValgusHammer toerheumatoid arthritisrheumatoid factor.

Identifiers

PMID41488442
PMCPMC12764324

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.