Evidence map›Paper›PMID 41488244›Full record

ReviewTurkish journal of medical sciences2025

Endocrine-disrupting chemicals in metabolic bone diseases, including osteoporosis.

Betül Gündüz, Elif Kiliç Kan, Ayşegül Atmaca

Abstract readReview
In one paragraph

Review in Turkish journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Betül GündüzDivision of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkiye.ORCID https://orcid.org/0000-0002-3945-2501
Elif Kiliç KanDivision of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkiye.ORCID https://orcid.org/0000-0002-9047-3121
Ayşegül AtmacaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkiye.ORCID https://orcid.org/0000-0001-6326-6365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine disruptors are chemical substances widely utilized across various industrial sectors. Due to their structural similarity to natural ligands, they bind to receptors and influence the endocrine system via agonist-antagonist mechanisms. Exposure occurs through the consumption of contaminated food and water, inhalation of polluted air and dust, and dermal contact. Owing to their dynamic remodeling capacity, bones represent potential targets for endocrine-disrupting chemicals. These chemicals can disrupt bone formation, skeletal development, hormonal regulation, and calcium metabolism. Sensitivity to endocrine-disrupting chemicals is greatest during the prenatal and early postnatal periods. This review summarizes the effects of endocrine-disrupting chemicals on bone tissue.

Indexed as

Bone Diseases, MetabolicEndocrine DisruptorsOsteoporosisAnimalsBone and BonesHumansEndocrine DisruptorsboneEndocrine-disrupting chemicalsosteoporosis

Identifiers

PMID41488244
PMCPMC12758924

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.