Evidence map›Paper›PMID 41488228›Full record

ArticleF1000Research2025

The Effect of Coconut and Frankincense Oils on the Biofilm Growth of

Nada Alghamdi, Lama Alshamrani, Safa Alboryah, Jomana Fayez Alsenan, Turki Alshehri, Naif N Abogazalah, Abdulrahman A Balhaddad

Registry-linked trialAbstract read
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In one paragraph

Article in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07535229 (The Efficiency of Frankincense and Other Extracts in the Treatment of Mild to Moderate Plaque Biofilm Induced Gingivitis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07535229 nacompletednot on this mapstarted 2026, after this paper: background citation

The Efficiency of Frankincense and Other Extracts in the Treatment of Mild to Moderate Plaque Biofilm Induced Gingivitis: a Double Blinded Randomized Controlled Trial.

TypeinterventionalSponsorOman Dental CollegeRan2026 to 2026Enrolled99ConditionsGingivitisArmsFrankinscence and coconut Oil based mouthwash, Frankinscence and Thyme essence/ water based mouthwash, Chlorhexidine (0.2%)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nada AlghamdiCollege of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Lama AlshamraniCollege of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Safa AlboryahCollege of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Jomana Fayez AlsenanDepartment of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.ORCID https://orcid.org/0009-0001-2040-4024
Turki AlshehriDepartment of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.ORCID https://orcid.org/0000-0001-7575-1587
Naif N AbogazalahDepartment of Restorative Dental Sciences, College of Dentistry, King Faisal University, Al Ahsa, 31982, Saudi Arabia.
Abdulrahman A BalhaddadDepartment of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.ORCID https://orcid.org/0000-0001-6678-7940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to investigate the antibiofilm effect of coconut and frankincense oils. Methods: Different types of coconut (organic refined, cocos nucifera, organic virgin, and organic extra virgin) and frankincense (frankincense pure essential oil in fractionated coconut oil and uplifting frankincense pure essential) oils were investigated. Serial dilutions (1:3, 1:6, 1:12, 1:24, 1:48, 1:96, and 1:192) were created from each oil and incubated with an overnight culture of Results: The greatest biofilm inhibition was observed in the uplifting frankincense pure essential oil at 1:3 dilution (0.67±0.12), which was significantly lower ( Conclusions: Organic refined, organic virgin, and extra virgin coconut oils, and uplifting frankincense essential oil, effectively reduced

Indexed as

Anti-Bacterial AgentsBiofilmsCoconut OilCocosFrankincenseOils, VolatilePlant OilsStreptococcus mutansMicrobial Sensitivity TestsAnti-Bacterial AgentsCoconut OilFrankincenseOils, VolatilePlant OilsEssential oils; biofilm; caries; gingivitis; mouthrinse.

Identifiers

PMID41488228
PMCPMC12759288

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.