Evidence map›Paper›PMID 41488214›Full record

ArticleGlobal health & medicine2025

Optimization of cefepime dosage regimens for

Fumiya Ebihara, Takumi Maruyama, Hidefumi Kasai, Mitsuru Shiokawa, Nobuaki Matsunaga, Yukihiro Hamada

Abstract readLetter
In one paragraph

Article in Global health & medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fumiya EbiharaDepartment of Pharmacy, Tokyo Women's Medical University Hospital, Tokyo, Japan.
Takumi MaruyamaDepartment of Pharmacy, Kochi Medical School Hospital, Nankoku-shi, Kochi, Japan.
Hidefumi KasaiLaboratory of Pharmacometrics and Systems Pharmacology Keio Frontier Research and Education Collaboration Square (K-FRECS) at Tonomachi, Keio University, Kawasaki, Kanagawa, Japan.
Mitsuru ShiokawaDepartment of Pharmacy, Tokyo Women's Medical University Hospital, Tokyo, Japan.
Nobuaki MatsunagaAMR Clinical Reference Center, National Center for Global Health and Medicine Hospital, Tokyo, Japan.
Yukihiro HamadaDepartment of Pharmacy, Kochi Medical School Hospital, Nankoku-shi, Kochi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Japan, the approved maximum daily dose of cefepime (4 g) is lower than international standards (6 g), potentially compromising efficacy against

Indexed as

cefepimeMonte Carlo simulationspharmacokinetics/pharmacodynamicssepsis

Identifiers

PMID41488214
PMCPMC12757317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.