ArticleFrontiers in medicine2025
Predicting cerebral infarction in COPD patients: an individualized nomogram based on arterial oxygen saturation.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the correlation between arterial oxygen saturation (SaO Methods: This retrospective study analyzed the clinical data of 846 COPD patients admitted to the Affiliated Hospital of Guangdong Medical University from June 2018 to December 2019. Logistic regression analysis was used to identify risk factors for CI, and the Wald chi-square test was applied to select predictors for inclusion in the nomogram. The performance of the model was evaluated and internally validated. External validation was conducted using data from 290 COPD patients prospectively enrolled at the Second Affiliated Hospital of Guangdong Medical University between January and October 2024. Results: A total of 846 COPD patients were included, with 592 assigned to the training cohort and 254 to the internal validation cohort. Predictive factors incorporated into the nomogram included systemic immune-inflammation index (SII), age, hypertension, cardiovascular disease (CVD), paraplegia, and SaO Conclusion: COPD is prone to cerebral infarction, and we verified the relationship between COPD and cerebral infarction through a visualogram model. The incidence of cerebral infarction in COPD patients is affected by systemic immune-inflammatory index (SII), age, hypertension, cardiovascular disease (C), hemiplegia, and SaO
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