ArticleFrontiers in medicine2025
The relationship between preoperative hypoalbuminemia and postoperative subsyndromal delirium in elderly hip fracture patients: a prospective study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Nomogram for subsyndromal delirium after cardiac surgery with cardiopulmonary bypass: a retrospective cohort study.Frontiers in medicine · 2026Article
- Postoperative delirium risk in elderly high-risk patients undergoing hip and knee arthroplasty (ASA Ⅲ-Ⅳ): construction and validation of a nomogram model based on frail frailty index.Frontiers in medicine · 2026Article
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8 authors.
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Abstract
Background: This study aimed to assess the prevalence of preoperative hypoalbuminemia in patients with hip fractures at Honghui Hospital, Xi'an Jiaotong University, and to examine its associations with postoperative subsyndromal delirium (SSD) and postoperative discharge-status. Methods: A prospective study was conducted at Honghui Hospital, Xi'an Jiaotong University, involving patients who underwent hip fracture surgery between October 2023 and March 2024. Data on demographics, comorbidities, preoperative serum albumin levels, SSD occurrence, and postoperative discharge status were also collected. Hypoalbuminemia was defined as serum albumin levels below 35 g/L. Results: In total, 279 patients were included in the analysis. Hypoalbuminemia was observed in 60 patients (21.51%) and 114 patients (40.86%) exhibited postoperative SSD. Multivariate logistic regression analysis revealed that diabetes mellitus (OR = 2.93, Conclusion: Our study identified a 21.51% prevalence of preoperative hypoalbuminemia in elderly patients undergoing hip fracture surgery, which independently contributed to an increased risk of postoperative SSD. We recommend implementing preoperative interventions to correct hypoalbuminemia.
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