ArticleFrontiers in medicine2025
Association between preoperative anxiety and ciprofol requirements in women undergoing surgical abortion: a prospective observational study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the association between preoperative anxiety level and ciprofol consumption in patients undergoing surgical abortion. Methods: A total of 144 patients scheduled for surgical abortion were enrolled and completed both the State-Trait Anxiety Inventory (STAI) and the Self-Rating Anxiety Scale (SAS). Anesthesia was induced with 5 μg/kg alfentanil and 0.3 mg/kg ciprofol. Additional ciprofol (0.1 mg/kg each) was administered as needed to maintain adequate anesthetic depth. The primary outcomes were the total ciprofol dose and State Anxiety (S-STAI) score. Secondary outcomes included the Trait Anxiety (T-STAI) and SAS scores, induction time, awakening time, baseline hemodynamic profiles, and the incidence of adverse events. Results: Preoperative anxiety levels (S-STAI) were weakly and positively associated with total ciprofol dose ( Conclusion: Preoperative anxiety showed a modest association with ciprofol requirements and induction time. These results indicate that anxiety may be a relevant factor to consider during sedation management for surgical abortion. Clinical trial registration: ChiCTR2500108366 (Chinese Clinical Trial Registry, www.chictr.org.cn).
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