Evidence map›Paper›PMID 41488027›Full record

ArticleCardiology research2025

Preliminary Observations on Discordance Between Coronary Artery Calcium Score of Zero and Coronary Computed Tomography Angiography Findings in Asymptomatic Adults.

Farhan Ashraf, Mohammad Raza Qureshi, Masoud Alam, Sushma Umroa, Shafaath Husain, Faiz Ul Amin, Munir Khan

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Article in Cardiology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Farhan AshrafLife Core Private Clinic, Abu Dhabi, United Arab Emirates.ORCID https://orcid.org/0000-0003-3734-837X
Mohammad Raza QureshiLife Core Private Clinic, Abu Dhabi, United Arab Emirates.
Masoud AlamLife Core Private Clinic, Abu Dhabi, United Arab Emirates.
Sushma UmroaLife Core Private Clinic, Abu Dhabi, United Arab Emirates.
Shafaath HusainLife Core Private Clinic, Abu Dhabi, United Arab Emirates.
Faiz Ul AminLife Core Private Clinic, Abu Dhabi, United Arab Emirates.
Munir KhanLife Core Private Clinic, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronary artery calcium (CAC) scoring is widely used to screen for coronary artery disease (CAD) in asymptomatic individuals. However, it detects calcified plaques and may miss non-calcified or soft plaques. This study compared the diagnostic accuracy of CAC scoring with coronary computed tomography angiography (CCTA) for detecting CAD in asymptomatic individuals with risk factors. Methods: Eighteen asymptomatic adults with a CAC score of 0 underwent CCTA to evaluate for subclinical CAD. Clinical, biochemical, and lifestyle risk factors were assessed. Diagnostic agreement between CAC and CCTA was analyzed using the Wilcoxon signed rank test. Results: The cohort had a mean age of 51.4 ± 10.6 years, 88.8% were male, and mean body mass index (BMI) was 27.7 ± 3.6 kg/m Conclusions: CCTA detected non-calcified atherosclerosis missed by CAC and demonstrated superior sensitivity for early CAD detection in asymptomatic individuals.

Indexed as

Coronary artery calcium scoringCoronary artery diseaseCoronary computed tomography angiographySensitivitySpecificityWilcoxon signed rank test

Identifiers

PMID41488027
PMCPMC12758033

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