Evidence map›Paper›PMID 41488017›Full record

ReviewTransboundary and emerging diseases2026

Innovative Chorioallantoic Membrane Model as Valuable Tool in Diagnostics and Testing of Domestic Animal Cancers.

Anna Sczasny, Jerzy Gubernator, Anna Jaromin, Nanhua Chen

Abstract readReview
In one paragraph

Review in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna SczasnyCenter for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, 44-102, Gliwice, Poland, onkologia.krakow.pl.ORCID https://orcid.org/0009-0001-6231-8597
Jerzy GubernatorDepartment of Lipids and Liposomes, Faculty of Biotechnology, University of Wrocław, 50-383, Wrocław, Poland, uni.wroc.pl.ORCID https://orcid.org/0000-0001-5925-8178
Anna JarominDepartment of Lipids and Liposomes, Faculty of Biotechnology, University of Wrocław, 50-383, Wrocław, Poland, uni.wroc.pl.ORCID https://orcid.org/0000-0002-7921-8007
Nanhua ChenCenter for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, 44-102, Gliwice, Poland, onkologia.krakow.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, particular attention has been paid to the possible connections, similarities, and potential uses of animals, especially pets (dogs and cats), in research on the causes, characteristics, and treatment of cancers occurring in pets and humans. One of the most promising experimental research models used to explore these issues is the avian embryo chorioallantoic membrane (CAM). This review aims to highlight the problem of the occurrence of cancers in domestic animals, placing emphasis on types, incidence, and predispositions of dogs and cats. Methodology and applications in cancer studies of this unique model were presented in detail. Moreover, the advantages and disadvantages of this diagnostic tool, as well as potential and future perspectives, were also described. This review confirms that cancer research can be conducted without the use of animals. Furthermore, the CAM can provide a robust and reliable model for this type of research and provide translational potential as an ethical, cost-effective model bridging laboratory and clinical research.

Indexed as

Cat DiseasesChorioallantoic MembraneDisease Models, AnimalDog DiseasesNeoplasmsAnimalsCatsChick EmbryoDogsanimal cancersCAMchicken embryoschorioallantoic membranein ovo/ex ovo model

Identifiers

PMID41488017
PMCPMC12764293

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.