ArticleFrontiers in cell and developmental biology2025
Optimized protocols for generating half-sized embryos from separated first two blastomeres in green sea urchin and
Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Embryonic scaling: morphogen gradients, size sensing, and scaler genes.Frontiers in cell and developmental biology · 2026Review
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6 authors.
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Abstract
The ability to restore normal body proportions after size reduction is a remarkable feature of early development. At the dawn of experimental embryology, Hans Driesch demonstrated that separated sea urchin blastomeres can develop into fully proportioned organisms, revealing an intrinsic capacity for embryonic scaling. However, the molecular mechanisms that enable this phenomenon remain poorly understood. Modern investigations of scaling, particularly those relying on bulk omics approaches, require reliable methods for producing large numbers of embryos that differ in size from wild-type embryos. Here, we present optimized protocols for generating half-sized embryos from separated blastomeres in two phylogenetically distant model organisms: the green sea urchin (
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