Evidence map›Paper›PMID 41487995›Full record

ReviewFrontiers in cellular neuroscience2025

Parvalbumin interneurons: the dark and bright sides of a key playmaker of neural circuits and behavior.

Eesha Wirk, Charles Quairiaux, Thomas Marissal

Abstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eesha WirkINMED, INSERM, Aix-Marseille University, Marseille, France.
Charles QuairiauxDepartment of Basic Neuroscience, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Thomas MarissalINMED, INSERM, Aix-Marseille University, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With their morphological and electrophysiological properties as well as exceptional connectivity, parvalbumin interneurons play a major role in the dynamics of the neural circuits of the hippocampus and cortex, along with associated cognitive functions. Their dysfunction, which is sometimes reversible, contributes to significant disruptions in network activity and behavioral deficits related to various diseases such as epilepsies or neuropsychiatric disorders. In this Mini Review, we present these parvalbumin interneurons, their characteristics, pathophysiological roles, and propose avenues for future investigations.

Indexed as

behaviorcircuitscortexdiseasehealthhippocampusmemoryparvalbumin interneurons

Identifiers

PMID41487995
PMCPMC12757226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.