Evidence map›Paper›PMID 41487945›Full record

ArticleResuscitation plus2026

Physical, psychological, cognitive, social health outcomes, and health-related quality of life in out-of-hospital cardiac arrest survivors and co-survivors: 3-month outcomes from the Quality Cardiac Arrest Survivorship cohort study (QualiCAS).

Pin Pin Pek, Kexin Fang, Shir Lynn Lim, Felix Maverick Rubillar Uy, Vui Kian Ho, Yew Woon Chia, Jia Min Chua, Ee Ling Goh, Le Xuan Liew, Christina Chen and 14 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Pin Pin PekPre-hospital & Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore.
Kexin FangDuke-NUS Medical School, Singapore.
Shir Lynn LimPre-hospital & Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore.
Felix Maverick Rubillar UyDepartment of Cardiology, Changi General Hospital, Singapore.
Vui Kian HoDepartment of Intensive Care Medicine, Sengkang General Hospital, Singapore.
Yew Woon ChiaCardiac Intensive Care Unit, Department of Cardiology, Tan Tock Seng Hospital, Singapore.
Jia Min ChuaDepartment of Cardiology, Khoo Teck Puat Hospital, Singapore.
Ee Ling GohEmergency Medicine Department, Ng Teng Fong General Hospital, Singapore.
Le Xuan LiewDepartment of Emergency Medicine, Singapore General Hospital, Singapore.
Christina ChenPre-hospital & Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore.
Nan LuoYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Kai Yi LeeYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Han Nee GanAccident & Emergency, Changi General Hospital, Singapore.
Benjamin Sieu-Hon LeongEmergency Medicine Department, National University Hospital, Singapore.
Desmond Ren-Hao MaoDepartment of Acute & Emergency Care, Khoo Teck Puat Hospital, Singapore.
Nausheen Edwin DoctorDepartment of Emergency Medicine, Sengkang General Hospital, Singapore.
Wei Ming NgEmergency Medicine Department, Ng Teng Fong General Hospital, Singapore.
Ying Zi OhDepartment of Cardiology, Changi General Hospital, Singapore.
Kah Hua PeckDepartment of Cardiology, Khoo Teck Puat Hospital, Singapore.
Michael Yih-Chong ChiaEmergency Department, Tan Tock Seng Hospital, Singapore.
Wei Ling TayEmergency Medicine Department, Ng Teng Fong General Hospital, Singapore.
Shun Yee LowDepartment of Emergency Medicine, Sengkang General Hospital, Singapore.
Marcus Eng Hock OngPre-hospital & Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore.
Andrew Fuwah HoPre-hospital & Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Survivors and co-survivors of out-of-hospital cardiac arrest (OHCA) experience disruptions in returning to normality. There is limited understanding of OHCA-related sequelae and their impact on co-survivors. This study describes the 3-month post-discharge health outcomes among OHCA survivors and co-survivors in the Quality Cardiac Arrest Survivorship cohort study (QualiCAS). Methods: We conducted a prospective, population-based cohort study, enrolling subjects from 1 February 2023 to 30 November 2024. Physical, psychological, cognitive, and social health, health-related quality of life (HRQoL), and caregiver burden were described separately for survivors and co-survivors. HRQoL of survivors and co-survivors was compared against age-, sex-, and ethnicity-adjusted Singapore population norm for EQ-5D-5L. Results: 62 survivors and 36 co-survivors completed 3-month assessments. 9.7 %, 6.5 %, 3.6 % of survivors screened positive for anxiety, depression, and post-traumatic stress disorder (PTSD), respectively. Survivors experienced mild cognitive impairment (43.1 %), impaired mobility (41.1 %), and weak muscle strength (39.7 %). Functional independence was high, and 73.9 % of survivors returned to employment. Survivors' HRQoL was lower compared to the general population (0.90 vs. 0.96). Co-survivors reported experiencing caregiving burden (41.7 %), with 22.2 %, 11.1 % and 6.1 % screening positive for anxiety, depression, and PTSD, respectively. Co-survivors' HRQoL was comparable to the general population (0.94 vs. 0.94). Conclusion: A significant subset of OHCA survivors experienced limitations in physical and cognitive functioning and return to work, and lower HRQoL. Psychological distress and caregiving burden were high among co-survivors. Our findings underscore the importance of systematic assessments of multi-dimensional aspects of health and referral to multi-component rehabilitation for both survivors and co-survivors.

Indexed as

AnxietyCardiac arrest survivorshipCaregiver burdenCaregiversCo-survivorsDepressionHealth-related quality of lifeOut-of-hospital cardiac arrestPost-traumatic stress disorderSurvivors

Identifiers

PMID41487945
PMCPMC12756648

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.