Evidence map›Paper›PMID 41487941›Full record

ArticleFrontiers in sports and active living2025

The "Menopause" knockout; a science-backed therapeutic ally, and strategy for midlife wellness.

Gayathri Delanerolle, Peter Phiri, Sohier Elneil

Abstract read
In one paragraph

Article in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gayathri DelanerolleInstitutes of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Peter PhiriClinical Trials Facility, Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, United Kingdom.
Sohier ElneilInstitute of Womens Health, University College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Boxing, traditionally a competitive sport, is increasingly recognised as a therapeutic exercise modality for women transitioning through perimenopause and menopause a life stage characterised by hormonal changes that can accelerate muscle loss, bone demineralisation, balance impairment, cardiovascular risk, weight gain, and mood fluctuations. Structured, non-contact fitness boxing integrates resistance, impact, and aerobic components, delivering multi-system benefits relevant to this population. Physically, boxing stimulates muscle protein synthesis, preserves lean mass, and provides weight-bearing stimuli to maintain bone density, thereby reducing fracture risk. Dynamic footwork and agility drills challenge proprioception and postural control, improving balance and lowering fall risk. The high-intensity cardiovascular demands enhance heart health, reduce blood pressure, improve lipid profiles, and assist with weight management. Physiologically, boxing's combined strength-endurance format boosts basal metabolic rate, improves insulin sensitivity, and moderates stress hormone levels, supporting metabolic health and resilience to menopause-related changes. Neuromuscular adaptations from complex motor sequences enhance coordination, reaction time, and functional independence. Neurologically, boxing promotes endorphin release and modulates key neurotransmitters such as serotonin and dopamine, improving mood stability and reducing anxiety. Cognitive engagement through learning and executing punch combinations enhances brain-derived neurotrophic factor (BDNF) levels, supporting neuroplasticity, memory, and executive function. Emerging evidence positions non-contact boxing as a safe, engaging, and multi-dimensional exercise strategy for midlife women. It addresses physical, physiological, and neurocognitive domains in one intervention, offering healthcare and wellness professionals a practical, evidence-informed tool to promote strength, stability, cardiovascular fitness, and psychological well-being during the menopausal transition.

Indexed as

boxingmenopausescience-Backed therapeutic allystrategy for midlife wellnesswomen

Identifiers

PMID41487941
PMCPMC12756445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.