ArticleCureus2025
Hereditary Persistence of Fetal Hemoglobin Presenting With 100% Fetal Hemoglobin and Recurrent Thrombotic Events.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fetal hemoglobin (HbF) is the predominant hemoglobin during fetal development, typically replaced by adult hemoglobin after birth. Elevated HbF levels in adulthood are rare and often associated with genetic conditions such as hereditary persistence of fetal hemoglobin (HPFH) or hemoglobinopathies. We present the case of a 30-year-old Pakistani male with 100% HbF, recurrent thrombotic events, including splenic thrombosis and unprovoked pulmonary embolism, and chronic systemic symptoms. Despite extensive evaluation, including bone marrow biopsy, advanced imaging, and multidisciplinary consultations, establishing a definitive diagnosis remained challenging. Genetic testing revealed a homozygous Asian-Indian deletion-inversion in the
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