Evidence map›Paper›PMID 41487860›Full record

ArticleCureus2025

Two Cases of Giant Uterine Leiomyomas With Myomatous Erythrocytosis Syndrome Treated by Laparoscopic Hysterectomy.

Noritoshi Aimoto, Takashi Matsumoto, Yonosuke Tsuda, Hosokawa Yumi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Noritoshi AimotoGynecology, Osaka Central Hospital, Osaka, JPN.
Takashi MatsumotoGynecology, Osaka Central Hospital, Osaka, JPN.
Yonosuke TsudaGynecology, Osaka Central Hospital, Osaka, JPN.
Hosokawa YumiGynecology, Osaka Central Hospital, Osaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myomatous erythrocytosis syndrome (MES) is a rare condition characterized by erythrocytosis, the presence of uterine leiomyomas, and the rapid normalization of hematologic parameters following tumor removal. Ectopic erythropoietin (EPO) production by the tumor is considered the main cause. We encountered two postmenopausal women with giant uterine leiomyomas complicated by MES. Case 1 involved a 21-cm subserosal leiomyoma, and Case 2 involved a 14-cm intramural leiomyoma. We performed total laparoscopic hysterectomy with in-bag morcellation in both cases, enabling safe specimen retrieval. Postoperatively, hemoglobin, hematocrit, and serum EPO levels decreased promptly. Despite the large tumor size, both patients showed only upper-normal serum EPO concentrations, suggesting that tumor weight does not necessarily correlate with EPO secretion.

Indexed as

erythropoietinerythropoietin producing uterine myomamyomatous erythrocytosis syndrometlhtotal laparoscopic hysterectomy

Identifiers

PMID41487860
PMCPMC12758228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.