ArticleCureus2025
Histological, Cytological, and Radiological Correlation in Thyroid Lesions.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroid disorders are among the most common endocrine diseases, with lesions ranging from benign nodules to malignant neoplasms. Accurate preoperative diagnosis is crucial for appropriate management. Fine-needle aspiration cytology (FNAC) is a widely used diagnostic tool, while ultrasonography (USG) and histopathology provide valuable adjunctive information. Correlating these modalities enhances diagnostic accuracy and clinical decision-making.
objectivesTo evaluate the cytological, histopathological, and radiological correlation in thyroid lesions and determine the diagnostic accuracy of FNAC and Thyroid Imaging Reporting and Data System (TIRADS) in differentiating benign and malignant thyroid nodules. METHODOLOGY: This cross-sectional, observational study was conducted in the Department of Pathology at Gandhi Medical College and Associated Hospitals, Bhopal, from May 2023 to October 2024, following approval of the ethics committee. A total of 150 samples from patients presenting with thyroid swellings were included in the study. All patients underwent clinical evaluation, thyroid function testing, USG (classified using the TIRADS system), and FNAC. Surgical specimens were subjected to histopathological examination wherever available. Results: The majority of patients were middle-aged females, with a female-to-male ratio of 4.6:1. The majority of lesions were benign, with colloid goiter being the most common diagnosis (40, 26.7%), followed by lymphocytic thyroiditis (17, 11.3%) and nodular goiter (15, 10%). On USG, most nodules were TIRADS 2 (58, 38.7%) and TIRADS 3 (63, 42%), while all TIRADS 5 lesions were malignant on histopathology (
conclusionsThe integration of cytological, radiological, and histopathological evaluation significantly improves the diagnostic precision of thyroid lesions. FNAC remains a simple, cost-effective, and reliable first-line investigation, while TIRADS scoring effectively stratifies the risk of malignancy. The combined use of these modalities facilitates accurate diagnosis, rational surgical intervention, and optimal patient management.
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