Evidence map›Paper›PMID 41487726›Full record

ArticleCureus2025

Integrating Cranio-Cervical Neuromyofascial Continuity With Body-Wide Function in Kimmerle Anomaly: An Osteopathic Case Report.

Gianfranco Pizzolorusso, Vito Borraccia, Cosimo Quaranta, Giandomenico D'Alessandro, Christian Lunghi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gianfranco PizzolorussoResearch Department, A.T. Still Academy, Grottaglie, ITA.
Vito BorracciaResearch Department, A.T. Still Academy, Grottaglie, ITA.
Cosimo QuarantaResearch Department, A.T. Still Academy, Grottaglie, ITA.
Giandomenico D'AlessandroResearch Department, A.T. Still Academy, Grottaglie, ITA.
Christian LunghiResearch Department, BMS Formation, Paris, FRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kimmerle anomaly is a congenital bony variant of the atlas vertebra that can, in rare cases, be associated with neurological and vascular symptoms. Although often asymptomatic, its clinical significance increases when presenting alongside persistent cranio-cervical pain and associated symptoms. This case report aims to describe the clinical presentation and osteopathic management of a young adult with symptoms potentially secondary to Kimmerle anomaly, highlighting the role of osteopathic manipulative treatment in a complex diagnostic context. A 19-year-old male presented with chronic cranio-cervical pain, right-sided neck and trapezius discomfort, tension-type headaches, dizziness, and episodic right-ear tinnitus and hypoacusis. Symptoms began at the age of 16 years and persisted despite various conservative interventions. Imaging revealed a complete Kimmerle anomaly. Neurological examination by the osteopath indicated altered sensation and sensory deficits. The patient underwent five osteopathic manipulative treatment sessions using a whole-body approach, focused on somatic dysfunctions, including, but not limited to, the upper cervical spine and its related fascial system connections. Techniques were chosen based on clinical evaluation and adapted to the patient's individual dysfunction patterns. No adverse effects were reported. At follow-up, the patient reported a reduction in pain, improved quality of life, and resolution of vestibular and auditory symptoms. This case highlights the potential value of osteopathic assessment and treatment in patients with persistent symptoms potentially linked to Kimmerle anomaly. The integration of osteopathic care into interdisciplinary diagnostic pathways may enhance management and improve outcomes in complex cases where structural anomalies coexist with functional disturbances.

Indexed as

arcuate foramencervical atlasosteopathic careosteopathic medicineponticulus posteriorsomatic dysfunctiontertiary prevention

Identifiers

PMID41487726
PMCPMC12757700

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