Evidence map›Paper›PMID 41487555›Full record

ArticleProceedings (Baylor University. Medical Center)

Unmasking the risk: euglycemic diabetic ketoacidosis induced by GLP-1 agonist in type 2 diabetes.

Parth Adrejiya, Ensaf Alhujaily, Mohammad Abubaker, Chelsae Dorenbush, Rami Khouzam

Abstract readCase Reports
In one paragraph

Article in Proceedings (Baylor University. Medical Center). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Parth AdrejiyaDepartment of Internal Medicine, Wellstar Spalding Medical Center, Griffin, Georgia, USA.ORCID https://orcid.org/0000-0003-1925-0563
Ensaf AlhujailyDepartment of Internal Medicine, Wellstar Spalding Medical Center, Griffin, Georgia, USA.
Mohammad AbubakerDepartment of Internal Medicine, Wellstar Spalding Medical Center, Griffin, Georgia, USA.
Chelsae DorenbushDepartment of Internal Medicine, Wellstar Spalding Medical Center, Griffin, Georgia, USA.
Rami KhouzamDepartment of Cardiology, Grand Strand Medical Center, Myrtle Beach, South Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Euglycemic diabetic ketoacidosis (EDKA) is a rare but serious complication of type 2 diabetes, traditionally linked to SGLT-2 inhibitors. We report a 59-year-old woman with type 2 diabetes and gastroparesis who discontinued SGLT-2 inhibitors 1 month earlier and developed EDKA shortly after initiating dulaglutide. She presented with nausea, vomiting, abdominal pain, and a modestly elevated glucose level. Laboratory findings confirmed EDKA, and she was successfully treated with intravenous insulin and fluids. Dulaglutide was discontinued, with no recurrence on follow-up. This case underscores the potential for GLP-1 receptor agonists to trigger EDKA in susceptible patients and the need for heightened clinical awareness.

Indexed as

Dulaglutideeuglycemic diabetic ketoacidosisgastroparesisGLP-1 receptor agonisttype 2 diabetes mellitus

Identifiers

PMID41487555
PMCPMC12758207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.