Evidence map›Paper›PMID 41487516›Full record

ArticleFrontiers in pharmacology2025

Anti-inflammatory effect of a pimarane diterpenoid isolated from

Wei Zhao, Meng Li, Chuanqing Jia, Iftikhar Ali, Long Chen

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603505 (Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07603505 phase1completednot on this map

Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome (PCOS)

TypeinterventionalSponsorJinnah Sindh Medical UniversityRan2025 to 2026Enrolled116ConditionsPolycystic Ovarian Syndrome (PCOS), Infertility, Metabolic DisordersArmsHerbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei Zhao *The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Meng Li *Shandong Academy of Chinese Medicine, Jinan, China.
Chuanqing Jia *Shandong Academy of Chinese Medicine, Jinan, China.
Iftikhar AliDepartment of Chemistry, Karakoram International University, Gilgit, Pakistan.
Long ChenKey Laboratory for Natural Active Pharmaceutical Constituents Research in Universities of Shandong Province, School of Pharmaceutical Sciences, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As an important folk medicine in Pakistan, Methods: The GC-MS guided isolation of compound Results: Compound Conclusion: The present study indicates that compound

Indexed as

diterpenelipopolysaccharide-induced inflammationNepeta, network analysisNF-κB and PPARγ signaling pathwaysRAW264.7 cell line

Identifiers

PMID41487516
PMCPMC12756164

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.