Evidence map›Paper›PMID 41487470›Full record

ArticleGenes & diseases2026

The role of positive feedback loop between LINC00862 and RBM47 in hepatocellular carcinoma suppression.

Tao Guo, Yingying Jiang, Shunshun Zhu, Min Shi, Linying Sun, Juan Feng, Zhen Li, Cheng Gong

Abstract read
In one paragraph

Article in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tao GuoDepartment of Pathophysiology, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, Shandong 261053, China.
Yingying JiangSchool of Stomatology, Shandong Second Medical University, Weifang, Shandong 261053, China.
Shunshun ZhuDepartment of Pathophysiology, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, Shandong 261053, China.
Min ShiDepartment of Pathophysiology, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, Shandong 261053, China.
Linying SunDepartment of Functional Laboratory, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, Shandong 261053, China.
Juan FengSchool of Public Health, Wuhan University, Wuhan, Hubei 430072, China.
Zhen LiDepartment of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.
Cheng GongDepartment of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the dynamic interaction between long non-coding RNA (lncRNA) and RNA binding proteins is widely recognized as pivotal in the regulation of hepatocellular carcinoma (HCC), the precise underlying mechanisms and networks governing their effects remain elusive. Here, we have uncovered LINC00862, a novel lncRNA that exhibits pronounced down-regulation in HCC tissues and whose expression levels are linked positively to favorable HCC outcomes, as a function of tumor stage and size. Through functional assays, we have established the anti-tumor effects of LINC00862 on HCC processes such as proliferation, invasion, metastasis, and growth

Indexed as

Hepatocellular carcinomaHoogsteen pairLINC00862lncRNARBM47

Identifiers

PMID41487470
PMCPMC12757521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.