ReviewFrontiers in neurology2025
Emerging roles for interleukin-11 in the inflammatory response of intracerebral hemorrhage.
Review in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- NF-κB-dependent and independent inflammatory responses during acute HIV-1 infection in a model of human microglia.Frontiers in immunology · 2026Article
- RBM15 affects mitophagy in intracerebral hemorrhage by promoting E2F1 nuclear translocation via NXF1.Frontiers in immunology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Intracerebral hemorrhage (ICH) is a severe cerebrovascular disorder with high rates of disability and mortality. Secondary inflammatory responses are recognized as pivotal determinants of patient outcomes and neurological recovery. In recent years, interleukin-11 (IL11), an important member of the IL6 cytokine family, has attracted increasing attention for its role in various inflammatory diseases and neurological injuries. Emerging evidence indicates that IL11 expression undergoes significant alterations following ICH and participates in regulating immune cell activation, cytokine secretion, and blood-brain barrier integrity. Beyond its complex interactions with other inflammatory mediators, IL11 may also exert neuroprotective effects, thereby providing a novel theoretical basis for therapeutic interventions targeting post-ICH inflammation. This review systematically summarizes the expression dynamics, molecular mechanisms, and potential therapeutic implications of IL11 in the context of ICH-associated inflammation, with the aim of offering new insights into strategies for modulating inflammatory responses in ICH patients.
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