Evidence map›Paper›PMID 41487373›Full record

ReviewJournal of pain research2025

Effectiveness of Isokinetic Muscle Strength Training on Knee Osteoarthritis Patients: A Systematic Review with Meta-Analysis.

Bo-Ya Chang, Long Chen, Hui-Chao Xu, Jian-Heng Hao, Hai-Jun Wang

Abstract readReview
In one paragraph

Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Isokinetic analysis of muscle strength recovery after fixed-bearing unicompartmental knee arthroplasty in patients with anterior cruciate ligament deficiency].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bo-Ya ChangThe Second Clinical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi Province, 030619, People's Republic of China.
Long ChenThe Second Clinical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi Province, 030619, People's Republic of China.
Hui-Chao XuThe Second Clinical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi Province, 030619, People's Republic of China.
Jian-Heng Hao *Department of Clinical Medicine, Shanxi University of Medicine, Lvliang, Shanxi Province, 032200, People's Republic of China.
Hai-Jun Wang *The Second Clinical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi Province, 030619, People's Republic of China.ORCID 0000-0003-1930-6248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study systematically evaluated the effects of isokinetic muscle strength training (IMST) on pain, function, and muscle performance in patients with knee osteoarthritis (KOA). Patients and Methods: Randomized controlled trials comparing IMST with other interventions for KOA were searched across multiple international and Chinese databases up to January 2025. Two investigators independently screened literature, extracted data, and assessed risk of bias according to the Cochrane Handbook Version 6.1.0. The RevMan 5.4 software was used to perform the meta-analysis. Overall quality of evidence was rated using GRADE approach. Results: Nineteen RCTs involving 1386 patients were finally included. Three of which had high risk bias. Compared with other treatments, IMST showed a borderline improvement in Lysholm score (MD = 1.21, 95% CI: [-0.62, 3.04], Conclusion: IMST appears to improve pain and function in patients with KOA, but the overall certainty of evidence is limited. Further high-quality RCTs are needed to confirm these benefits and guide clinical practice.

Indexed as

GRADEIsokinetic exerciseknee osteoarthritismeta-analysisrandomized controlled trials

Identifiers

PMID41487373
PMCPMC12756960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.