Evidence map›Paper›PMID 41487296›Full record

ArticleFrontiers in reproductive health2025

Predictive value of hematological parameters for IVF success: a retrospective analysis.

Fatma Tulucu Kalkan, Ufuk Atlihan, Gökçe Aykanat, Begum Ertan, Ferruh Acet, Ege Nazan Tavmergen Goker, Erol Tavmergen

Abstract read
In one paragraph

Article in Frontiers in reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatma Tulucu KalkanTC Saglik Bakanligi Gaziantep Sehir Hastanesi, Şahinbey, Türkiye.
Ufuk AtlihanManisa Merkezefendi State Hospital, Manisa, Türkiye.
Gökçe AykanatKınık State Hospital, Izmir, Türkiye.
Begum ErtanAkhisar State Hospital, Manisa, Türkiye.
Ferruh AcetTavmergen IVF Clinic, Izmir, Türkiye.
Ege Nazan Tavmergen GokerEge Universitesi Tip Fakultesi, Izmir, Türkiye.
Erol TavmergenEge Universitesi Tip Fakultesi, Izmir, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the predictive value of hematologic inflammatory indices derived from complete blood count (CBC) parameters for Materials and methods: This retrospective cohort study included 430 women with unexplained infertility who underwent IVF/ICSI cycles at Ege University Hospital between January 2020 and January 2025. CBC parameters and derived systemic inflammatory indices-including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune-inflammation value (PIV)-were measured on the ovulation trigger day. Patients were divided into pregnant and non-pregnant groups according to clinical pregnancy outcomes. Demographic, hormonal, hematologic, and embryologic variables were compared using appropriate statistical tests, and logistic regression and ROC analyses were performed to identify independent predictors of pregnancy. Results: None of the CBC-derived inflammatory indices showed significant differences between pregnant and non-pregnant groups (all Conclusion: Systemic inflammatory indices derived from CBC parameters, including NLR, PLR, MLR, SII, SIRI, and PIV, do not predict IVF/ICSI outcomes in women with unexplained infertility. Embryologic parameters, especially 2PN and total embryo counts, remain the most reliable predictors of clinical pregnancy.

Indexed as

embryo qualityhematologic indicesinflammationIVFneutrophil-to-lymphocyte ratiosystemic immune-inflammation indexunexplained infertility

Identifiers

PMID41487296
PMCPMC12756499

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