Episodic Memories Bias Contextual Threat Inferences after Aerobic and Mind-Body Exercise.

Background and Aim: Contextual threat inference is the process by which latent environmental threat is recognized, a key component of memory which guides decision making. This study sought to interrogate the contribution of episodic memory towards contextual threat inference and determine if acute exercise, an intervention which impacts memory, could magnify the effects of memory on contextual threat inferences. Methods: Participants ( Results: Participants learned to differentiate contexts based on the unique combinations of conditioned stimuli and threat probabilities. During the threat inference task, recognized episodic memory probes biased contextual threat inferences, but only after participants completed moderate-intensity aerobic exercise or yoga. Recognition of the episodic memory probes was equal across exercise conditions. Conclusion: These findings provide novel support for the role of episodic memory on contextual threat inferences. There was evidence that moderate-intensity aerobic exercise and yoga impact associative ties between episodic memories and context. These results support neurocomputational models which integrate episodic memory with reinforcement learning and inform the cognitive processes through which exercise may impact contextual threat inference.