ReviewAnnals of medicine2026
Antimicrobial proteins regulating neuroinflammation.
Review in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Peptidoglycan recognition proteins in the brain: Role in neuroinflammation and behavioral consequences.Histology and histopathology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial peptides/proteins (AMPs), also termed host defense peptides, are well-known effector molecules in innate immunity across all organisms. Recent research has revealed that AMPs possess multifunctional properties beyond their antimicrobial activity, including roles in neuroinflammation. The expression of AMPs has been detected within the central nervous system (CNS) at a basal level and is generally upregulated in various neurological disorders. Owing to its expression and induction in the CNS, there has been growing interest in investigating the relationships among AMPs, neuroinflammation, and various neurological disorders.
methodsTo ensure a comprehensive overview, relevant articles were identified through an extensive PubMed search for this review. Here, we discuss recent literature and advances in understanding AMPs in the CNS at both molecular and functional levels. Additionally, the potential use of these proteins in targeting neuroinflammatory disorders is examined.
conclusionsOverall, this review provides insight into the complex interplay between AMPs and neuroinflammation and highlights the need for further research in this field.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.