Evidence map›Paper›PMID 41487010›Full record

ReviewCurrent pharmaceutical design2026

A Pharmacological Update and Safety Analysis of Medications for Smoking Cessation: Which Ones to Use?

Canan Akman, Feride Sinem Akgun, Betul Akbuga Ozel, Bilgen Ozkaya, Goksu Afacan Ozturk, Ozgur Karcioglu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Canan AkmanDepartment of Emergency Medicine, Canakkale Onsekiz Mart Universitesi, Canakkale, Turkiye.ORCID 0000-0002-3427-5649
Feride Sinem AkgunEmergency Medicine, Faculty of Medicine, Maltepe University, Istanbul, Türkiye.ORCID 0000-0001-6537-866X
Betul Akbuga OzelDepartment of Emergency Medicine, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkiye.ORCID 0000-0002-0460-6101
Bilgen OzkayaDepartment of Emergency Medicine, Losante Children's and Adult Hospital, Ankara, Turkiye.ORCID 0000-0003-1659-4723
Goksu Afacan OzturkDepartment of Emergency Medicine, Istanbul Aydın University, Istanbul, Turkiye.ORCID 0000-0002-2755-2660
Ozgur KarciogluDepartment of Emergency Medicine, University of Health Sciences, Istanbul Education and Research Hospital, Istanbul, Turkiye.ORCID 0000-0002-8814-6164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interventions to reduce smoking prevalence aim to help patients quit smoking to cut down its hazards and related impairments in human beings. Pharmacological treatments are recommended for those with high levels of addiction because of severe physical and psychological dependence. Use of pharmacotherapy can double the odds of successful quitting. Nicotine replacement therapy (NRT), drug treatment regimens including nicotinic receptor agonists (varenicline), dopamine and norepinephrine reuptake inhibitors (bupropion), cytisinicline (cytisine), and combination therapy (NRT + medication) can be employed on a case-by-case basis. Furthermore, varenicline has been found to be more effective than the other agents in most studies. The most common adverse effects of pharmacological agents include depression, nausea, anxiety, abnormal dreams, and insomnia. On the other hand, electronic cigarettes offer another alternative to aid in smoking cessation (SC). Endurance of SC is mostly related to the employment of combined approaches, such as counselling and pharmacotherapy. This study is designed to provide an up-to-date overview of the contemporary approach to interventions aimed at helping patients in SC.

Indexed as

Nicotinic AgonistsSmoking CessationSmoking Cessation AgentsBupropionHumansNicotine Replacement TherapyVareniclineBupropionNicotinic AgonistsSmoking Cessation AgentsVareniclinebupropioncytisiniclineelectronic cigarettesnicotine dependencenicotinic receptor agonistsSmoking cessationvarenicline

Identifiers

PMID41487010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.